> ## Documentation Index > Fetch the complete documentation index at: https://protocol.crunchdao.com/llms.txt > Use this file to discover all available pages before exploring further. # Use cases > How institutions use the Crunch Protocol across finance, science, and crypto. The Crunch Protocol has been validated in some of the most demanding quantitative environments. Below are production use cases that demonstrate the range of problems Coordinators can solve. ## Finance ### Cross-sectional asset ranking In collaboration with [ADIA Lab](https://www.adialab.ae/) (research arm of the Abu Dhabi Investment Authority), Crunch hosted cross-sectional asset ranking competitions for three consecutive years. * **Result**: Crunch models consistently achieved double-digit percentage improvements over the lab's best internal benchmarks * **Significance**: A decentralized contributor network outperformed a well-funded sovereign wealth research unit ### Structural break detection Also with [ADIA Lab](https://www.adialab.ae/), Crunch detected structural breaks in the market using models from the [Structural Break Crunch](https://hub.crunchdao.com/competitions/structural-break). ### Mid-market pricing and volatility prediction Mid+One™ is a high-frequency mid-market pricing engine built on Crunch. It bridges community research and institutional use cases, turning collective intelligence into a live inference engine operating in under 60 microseconds. It is currently live and being tested by major institutions for: * Mid-market pricing — models from the [Mid+One Crunch](https://hub.crunchdao.com/competitions/mid-one) * Volatility prediction — models from the [Falcon Crunch](https://hub.crunchdao.com/competitions/falcon) ## Science ### Autoimmune disease research In a competition organized by the [Broad Institute](https://www.broadinstitute.org/) of MIT and Harvard (Eric and Wendy Schmidt Center), Crunch models outperformed internal benchmarks on biomedical vision tasks — demonstrating that the protocol generalizes beyond finance. ### Metabolic disease research Together with the [Broad Institute](https://www.broadinstitute.org/), Crunch is crowdsourcing new approaches in the [Obesity ML](https://hub.crunchdao.com/competitions/broad-obesity-1) competition, where Crunchers tackle obesity prediction using real-world data. ## Crypto ### Powering Bittensor miners A Crunch Node powers miners on the [Synth Bittensor Subnet](https://www.synthdata.co/), enabling any ML engineer to participate in the Synth subnet through the Crunch Protocol. Diagram showing how the Synth Bittensor Subnet connects to the Crunch Protocol via a Crunch Node *** Each of these use cases proves a fundamental pattern: when diverse modeling approaches combine, individual limitations offset each other, creating solutions no single team could discover alone. Ready to create your own Crunch? Follow the getting started guide.